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Desynchronization of Circadian Clocks in Cancer: A Metabolic and Epigenetic Connection
Circadian clocks are innate oscillators that drive daily rhythms in metabolism, physiology, and behavior. 24-h rhythms in gene expression, driven by core clock transcription factors, reflect the epigenetic state of the cell, which in turn is dictated by the metabolic environment. Cancer cells alter...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474466/ https://www.ncbi.nlm.nih.gov/pubmed/28674522 http://dx.doi.org/10.3389/fendo.2017.00136 |