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Abl Tyrosine Kinase Regulates Hepatitis C Virus Entry

Abl is a central regulator of multiple cellular processes controlling actin dynamics, proliferation, and differentiation. Here, we showed that knockdown of Abl impaired hepatitis C virus (HCV) propagation. Treatment of Abl tyrosine kinase-specific inhibitor, imatinib and dasatinib, also significantl...

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Detalles Bibliográficos
Autores principales: Min, Saehong, Lim, Yun-Sook, Shin, Dongjo, Park, Chorong, Park, Jae-Bong, Kim, Seungtaek, Windisch, Marc P., Hwang, Soon B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474468/
https://www.ncbi.nlm.nih.gov/pubmed/28674529
http://dx.doi.org/10.3389/fmicb.2017.01129