Angiotensin-II-induced Muscle Wasting is Mediated by 25-Hydroxycholesterol via GSK3β Signaling Pathway

While angiotensin II (ang II) has been implicated in the pathogenesis of cardiac cachexia (CC), the molecules that mediate ang II's wasting effect have not been identified. It is known TNF-α level is increased in patients with CC, and TNF-α release is triggered by ang II. We therefore hypothesi...

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Detalles Bibliográficos
Autores principales: Shen, Congcong, Zhou, Jin, Wang, Xiaoxiao, Yu, Xi-Yong, Liang, Chun, Liu, Bin, Pan, Xiangbin, Zhao, Qiong, Song, Jenny Lee, Wang, Jiajun, Bao, Meiyu, Wu, Chaofan, Li, Yangxin, Song, Yao-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474518/
https://www.ncbi.nlm.nih.gov/pubmed/28161398
http://dx.doi.org/10.1016/j.ebiom.2017.01.040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474518/
https://www.ncbi.nlm.nih.gov/pubmed/28161398
http://dx.doi.org/10.1016/j.ebiom.2017.01.040

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