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Traumatic Brain Injury Induces Genome-Wide Transcriptomic, Methylomic, and Network Perturbations in Brain and Blood Predicting Neurological Disorders

The complexity of the traumatic brain injury (TBI) pathology, particularly concussive injury, is a serious obstacle for diagnosis, treatment, and long-term prognosis. Here we utilize modern systems biology in a rodent model of concussive injury to gain a thorough view of the impact of TBI on fundame...

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Detalles Bibliográficos
Autores principales: Meng, Qingying, Zhuang, Yumei, Ying, Zhe, Agrawal, Rahul, Yang, Xia, Gomez-Pinilla, Fernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474519/
https://www.ncbi.nlm.nih.gov/pubmed/28174132
http://dx.doi.org/10.1016/j.ebiom.2017.01.046