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Memory B Cells are Major Targets for Effective Immunotherapy in Relapsing Multiple Sclerosis

Although multiple sclerosis (MS) is considered to be a CD4, Th17-mediated autoimmune disease, supportive evidence is perhaps circumstantial, often based on animal studies, and is questioned by the perceived failure of CD4-depleting antibodies to control relapsing MS. Therefore, it was interestingly...

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Detalles Bibliográficos
Autores principales: Baker, David, Marta, Monica, Pryce, Gareth, Giovannoni, Gavin, Schmierer, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474520/
https://www.ncbi.nlm.nih.gov/pubmed/28161400
http://dx.doi.org/10.1016/j.ebiom.2017.01.042