KLF4 is regulated by RAS/RAF/MEK/ERK signaling through E2F1 and promotes melanoma cell growth

Melanoma is the most lethal form of skin cancer and treatment of metastatic melanoma remains challenging. BRAF/MEK inhibitors show only temporary benefit due the occurrence of resistance and immunotherapy is effective only in a subset of patients. To improve patient survival, there is a need to bett...

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Detalles Bibliográficos
Autores principales: Riverso, M, Montagnani, V, Stecca, B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474568/
https://www.ncbi.nlm.nih.gov/pubmed/28068326
http://dx.doi.org/10.1038/onc.2016.481

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474568/
https://www.ncbi.nlm.nih.gov/pubmed/28068326
http://dx.doi.org/10.1038/onc.2016.481

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