D-BMAP18 Antimicrobial Peptide Is Active In vitro, Resists to Pulmonary Proteases but Loses Its Activity in a Murine Model of Pseudomonas aeruginosa Lung Infection

The spread of antibiotic resistant-pathogens is driving the search for new antimicrobial compounds. Pulmonary infections experienced by cystic fibrosis (CF) patients are a dramatic example of this health-care emergency. Antimicrobial peptides could answer the need for new antibiotics but translating...

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Detalles Bibliográficos
Autores principales: Mardirossian, Mario, Pompilio, Arianna, Degasperi, Margherita, Runti, Giulia, Pacor, Sabrina, Di Bonaventura, Giovanni, Scocchi, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474674/
https://www.ncbi.nlm.nih.gov/pubmed/28674688
http://dx.doi.org/10.3389/fchem.2017.00040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474674/
https://www.ncbi.nlm.nih.gov/pubmed/28674688
http://dx.doi.org/10.3389/fchem.2017.00040

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