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Allosteric Control of Substrate Specificity of the Escherichia coli ADP-Glucose Pyrophosphorylase

The substrate specificity of enzymes is crucial to control the fate of metabolites to different pathways. However, there is growing evidence that many enzymes can catalyze alternative reactions. This promiscuous behavior has important implications in protein evolution and the acquisition of new func...

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Detalles Bibliográficos
Autores principales: Ebrecht, Ana C., Solamen, Ligin, Hill, Benjamin L., Iglesias, Alberto A., Olsen, Kenneth W., Ballicora, Miguel A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474683/
https://www.ncbi.nlm.nih.gov/pubmed/28674689
http://dx.doi.org/10.3389/fchem.2017.00041