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Precocious centriole disengagement and centrosome fragmentation induced by mitotic delay

The spindle assembly checkpoint (SAC) delays mitotic progression until all sister chromatid pairs achieve bi-orientation, and while the SAC can maintain mitotic arrest for extended periods, moderate delays in mitotic progression have significant effects on the resulting daughter cells. Here we show...

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Detalles Bibliográficos
Autores principales: Karki, Menuka, Keyhaninejad, Neda, Shuster, Charles B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474744/
https://www.ncbi.nlm.nih.gov/pubmed/28607478
http://dx.doi.org/10.1038/ncomms15803