An ubiquitin-dependent balance between mitofusin turnover and fatty acids desaturation regulates mitochondrial fusion

Mitochondrial integrity relies on homotypic fusion between adjacent outer membranes, which is mediated by large GTPases called mitofusins. The regulation of this process remains nonetheless elusive. Here, we report a crosstalk between the ubiquitin protease Ubp2 and the ubiquitin ligases Mdm30 and R...

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Detalles Bibliográficos
Autores principales: Cavellini, Laetitia, Meurisse, Julie, Findinier, Justin, Erpapazoglou, Zoi, Belgareh-Touzé, Naïma, Weissman, Allan M., Cohen, Mickael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474747/
https://www.ncbi.nlm.nih.gov/pubmed/28607491
http://dx.doi.org/10.1038/ncomms15832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474747/
https://www.ncbi.nlm.nih.gov/pubmed/28607491
http://dx.doi.org/10.1038/ncomms15832

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