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An ubiquitin-dependent balance between mitofusin turnover and fatty acids desaturation regulates mitochondrial fusion
Mitochondrial integrity relies on homotypic fusion between adjacent outer membranes, which is mediated by large GTPases called mitofusins. The regulation of this process remains nonetheless elusive. Here, we report a crosstalk between the ubiquitin protease Ubp2 and the ubiquitin ligases Mdm30 and R...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474747/ https://www.ncbi.nlm.nih.gov/pubmed/28607491 http://dx.doi.org/10.1038/ncomms15832 |