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Increasing mapping precision of genome-wide association studies: to genotype and impute, sequence, or both?

Fine-mapping to identify causal variants in genome-wide association studies remains challenging. A recent study provides guidance for future research.

Detalles Bibliográficos
Autores principales: Wang, Zhaoming, Chatterjee, Nilanjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474869/
https://www.ncbi.nlm.nih.gov/pubmed/28629446
http://dx.doi.org/10.1186/s13059-017-1255-6