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Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations

Several studies using genome-wide molecular techniques have reported various degrees of genetic heterogeneity between primary tumours and their distant metastases. However, it has been difficult to discern patterns of dissemination owing to the limited number of patients and available metastases. He...

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Detalles Bibliográficos
Autores principales: Brown, David, Smeets, Dominiek, Székely, Borbála, Larsimont, Denis, Szász, A. Marcell, Adnet, Pierre-Yves, Rothé, Françoise, Rouas, Ghizlane, Nagy, Zsófia I., Faragó, Zsófia, Tőkés, Anna-Mária, Dank, Magdolna, Szentmártoni, Gyöngyvér, Udvarhelyi, Nóra, Zoppoli, Gabriele, Pusztai, Lajos, Piccart, Martine, Kulka, Janina, Lambrechts, Diether, Sotiriou, Christos, Desmedt, Christine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5474888/
https://www.ncbi.nlm.nih.gov/pubmed/28429735
http://dx.doi.org/10.1038/ncomms14944