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Silencing of TRB3 Ameliorates Diabetic Tubule Interstitial Nephropathy via PI3K/AKT Signaling in Rats

BACKGROUND: Nephropathy, a chronic progressive kidney disease often characterized by glomeruli scarring and sclerosis, is a major complication of diabetes mellitus. Development of nephropathologic lesions has been shown to be associated with suppressed AKT phosphorylation and elevated level of apopt...

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Detalles Bibliográficos
Autores principales: Ma, Yali, Chen, Fang, Yang, Suxia, Duan, Yurui, Sun, Zhiqiang, Shi, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475374/
https://www.ncbi.nlm.nih.gov/pubmed/28600485
http://dx.doi.org/10.12659/MSM.902581