The bile acid receptor FXR attenuates acinar cell autophagy in chronic pancreatitis

The functional relationship between bile acid (BA) and autophagy has not been evaluated in the context of pancreatitis. Here we investigated whether BA and their nuclear farnesoid X receptor (FXR) modulate autophagy and the development of pancreatitis. FXR expression, autophagy, apoptosis and necrop...

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Detalles Bibliográficos
Autores principales: Zhou, Xiaodong, Xie, Li, Bergmann, Frank, Endris, Volker, Strobel, Oliver, Büchler, Markus W, Kroemer, Guido, Hackert, Thilo, Fortunato, Franco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475417/
https://www.ncbi.nlm.nih.gov/pubmed/28660075
http://dx.doi.org/10.1038/cddiscovery.2017.27

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5475417/
https://www.ncbi.nlm.nih.gov/pubmed/28660075
http://dx.doi.org/10.1038/cddiscovery.2017.27

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