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Uptake, biotransformation and elimination of selected pharmaceuticals in a freshwater invertebrate measured using liquid chromatography tandem mass spectrometry

Methods were developed to assess uptake and elimination kinetics in Gammarus pulex of nine pharmaceuticals (sulfamethazine, carbamazepine, diazepam, temazepam, trimethoprim, warfarin, metoprolol, nifedipine and propranolol) using targeted LC-MS/MS to determine bioconcentration factors (BCFs) using a...

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Detalles Bibliográficos
Autores principales: Miller, Thomas H., Bury, Nicolas R., Owen, Stewart F., Barron, Leon P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476196/
https://www.ncbi.nlm.nih.gov/pubmed/28554023
http://dx.doi.org/10.1016/j.chemosphere.2017.05.083