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Survival, bacterial clearance and thrombocytopenia are improved in polymicrobial sepsis by targeting nuclear transport shuttles

The rising tide of sepsis, a leading cause of death in the US and globally, is not adequately controlled by current antimicrobial therapies and supportive measures, thereby requiring new adjunctive treatments. Severe microvascular injury and multiple organ failure in sepsis are attributed to a “geno...

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Detalles Bibliográficos
Autores principales: Veach, Ruth Ann, Liu, Yan, Zienkiewicz, Jozef, Wylezinski, Lukasz S., Boyd, Kelli L., Wynn, James L., Hawiger, Jacek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476269/
https://www.ncbi.nlm.nih.gov/pubmed/28628637
http://dx.doi.org/10.1371/journal.pone.0179468