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Survival, bacterial clearance and thrombocytopenia are improved in polymicrobial sepsis by targeting nuclear transport shuttles
The rising tide of sepsis, a leading cause of death in the US and globally, is not adequately controlled by current antimicrobial therapies and supportive measures, thereby requiring new adjunctive treatments. Severe microvascular injury and multiple organ failure in sepsis are attributed to a “geno...
Autores principales: | Veach, Ruth Ann, Liu, Yan, Zienkiewicz, Jozef, Wylezinski, Lukasz S., Boyd, Kelli L., Wynn, James L., Hawiger, Jacek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476269/ https://www.ncbi.nlm.nih.gov/pubmed/28628637 http://dx.doi.org/10.1371/journal.pone.0179468 |
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