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Protein signature in cerebrospinal fluid and serum of Alzheimer’s disease patients: The case of apolipoprotein A-1 proteoforms

In the diagnosis of Alzheimer’s disease (AD) total tau (T-tau), tau phosphorylated at threonine 181 (P-tau181), and the 42 amino acid isoform of alpha β-amyloid (Aβ) are well established surrogate CSF markers. However, there is a constant need for new diagnostic markers to identify the disease at a...

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Detalles Bibliográficos
Autores principales: Fania, Chiara, Arosio, Beatrice, Capitanio, Daniele, Torretta, Enrica, Gussago, Cristina, Ferri, Evelyn, Mari, Daniela, Gelfi, Cecilia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476270/
https://www.ncbi.nlm.nih.gov/pubmed/28628634
http://dx.doi.org/10.1371/journal.pone.0179280