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Elimination of persistent vaccine bacteria of Salmonella enterica serovar Typhimurium in the guts of immunized mice by inducible expression of truncated YncE

Orally administered vaccine bacteria usually persist for a period of time in the intestinal tracts of immunized individuals, and are excreted in feces to the environment resulting in a potential biosafety issue. The releasing risk can be minimized by immediate elimination of the persistent vaccine b...

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Detalles Bibliográficos
Autores principales: Wang, Yiran, Li, Jianhua, Xiong, Kun, Chen, Zhijin, Zheng, Chunping, Tan, Yong, Cong, Yanguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476278/
https://www.ncbi.nlm.nih.gov/pubmed/28628661
http://dx.doi.org/10.1371/journal.pone.0179649