High-Dose Erythropoietin Population Pharmacokinetics in Neonates with Hypoxic-Ischemic Encephalopathy Receiving Hypothermia

BACKGROUND: High-dose erythropoietin (Epo) is a promising neuroprotective treatment in neonates with hypoxic ischemic encephalopathy (HIE) receiving hypothermia. We evaluated the pharmacokinetics and dose-exposure relationships of high-dose Epo in this population to inform future dosing strategies....

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Detalles Bibliográficos
Autores principales: Frymoyer, Adam, Juul, Sandra E., Massaro, An N., Bammler, Theo K, Wu, Yvonne W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476365/
https://www.ncbi.nlm.nih.gov/pubmed/28099423
http://dx.doi.org/10.1038/pr.2017.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476365/
https://www.ncbi.nlm.nih.gov/pubmed/28099423
http://dx.doi.org/10.1038/pr.2017.15

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