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Cystoviral RNA-directed RNA polymerases: Regulation of RNA synthesis on multiple time and length scales

P2, an RNA-directed RNA polymerase (RdRP), is encoded on the largest of the three segments of the double-stranded RNA genome of cystoviruses. P2 performs the dual tasks of replication and transcription de novo on single-stranded RNA templates, and plays a critical role in the viral life-cycle. Work...

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Detalles Bibliográficos
Autores principales: Alphonse, Sébastien, Ghose, Ranajeet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476504/
https://www.ncbi.nlm.nih.gov/pubmed/28104452
http://dx.doi.org/10.1016/j.virusres.2017.01.006