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Cystoviral RNA-directed RNA polymerases: Regulation of RNA synthesis on multiple time and length scales
P2, an RNA-directed RNA polymerase (RdRP), is encoded on the largest of the three segments of the double-stranded RNA genome of cystoviruses. P2 performs the dual tasks of replication and transcription de novo on single-stranded RNA templates, and plays a critical role in the viral life-cycle. Work...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier B.V.
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476504/ https://www.ncbi.nlm.nih.gov/pubmed/28104452 http://dx.doi.org/10.1016/j.virusres.2017.01.006 |