Nanoassembly routes stimulate conflicting antibody quantity and quality for transmission-blocking malaria vaccines

Vaccine development efforts have recently focused on enabling strong immune responses to poorly immunogenic antigens, via display on multimerisation scaffolds or virus like particles (VLPs). Typically such studies demonstrate improved antibody titer comparing monomeric and nano-arrayed antigen. Ther...

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Detalles Bibliográficos
Autores principales: Leneghan, Darren B., Miura, Kazutoyo, Taylor, Iona J., Li, Yuanyuan, Jin, Jing, Brune, Karl D., Bachmann, Martin F., Howarth, Mark, Long, Carole A., Biswas, Sumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476561/
https://www.ncbi.nlm.nih.gov/pubmed/28630474
http://dx.doi.org/10.1038/s41598-017-03798-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476561/
https://www.ncbi.nlm.nih.gov/pubmed/28630474
http://dx.doi.org/10.1038/s41598-017-03798-3

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