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A Novel Gd-DTPA-conjugated Poly(L-γ-glutamyl-glutamine)-paclitaxel Polymeric Delivery System for Tumor Theranostics

The conventional chemotherapeutics could not be traced in vivo and provide timely feedback on the clinical effectiveness of drugs. In this study, poly(L-γ-glutamyl-glutamine)-paclitaxel (PGG-PTX), as a model polymer, was chemically conjugated with Gd-DTPA (Gd-diethylenetriaminepentaacetic acid), a T...

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Detalles Bibliográficos
Autores principales: Gao, Lipeng, Zhou, Jinge, Yu, Jing, Li, Qilong, Liu, Xueying, Sun, Lei, Peng, Ting, Wang, Jing, Zhu, Jianzhong, Sun, Jihong, Lu, Weiyue, Yu, Lei, Yan, Zhiqiang, Wang, Yiting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476566/
https://www.ncbi.nlm.nih.gov/pubmed/28630436
http://dx.doi.org/10.1038/s41598-017-03633-9