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SMYD3 Promotes Homologous Recombination via Regulation of H3K4-mediated Gene Expression
SMYD3 is a methyltransferase highly expressed in many types of cancer. It usually functions as an oncogenic protein to promote cell cycle, cell proliferation, and metastasis. Here, we show that SMYD3 modulates another hallmark of cancer, DNA repair, by stimulating transcription of genes involved in...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476597/ https://www.ncbi.nlm.nih.gov/pubmed/28630472 http://dx.doi.org/10.1038/s41598-017-03385-6 |