Progesterone prevents epithelial-mesenchymal transition of ovine amniotic epithelial cells and enhances their immunomodulatory properties

The in vitro expansion is detrimental to therapeutic applications of amniotic epithelial cells (AEC), an emerging source of fetal stem cells. This study provides molecular evidences of progesterone (P(4)) role in preventing epithelial-mesenchymal transition (EMT) in ovine AEC (oAEC). oAEC amplified...

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Detalles Bibliográficos
Autores principales: Canciello, Angelo, Russo, Valentina, Berardinelli, Paolo, Bernabò, Nicola, Muttini, Aurelio, Mattioli, Mauro, Barboni, Barbara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476612/
https://www.ncbi.nlm.nih.gov/pubmed/28630448
http://dx.doi.org/10.1038/s41598-017-03908-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476612/
https://www.ncbi.nlm.nih.gov/pubmed/28630448
http://dx.doi.org/10.1038/s41598-017-03908-1

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