Overcoming evolved resistance to population-suppressing homing-based gene drives

The recent development of a CRISPR-Cas9-based homing system for the suppression of Anopheles gambiae is encouraging; however, with current designs, the slow emergence of homing-resistant alleles is expected to result in suppressed populations rapidly rebounding, as homing-resistant alleles have a si...

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Detalles Bibliográficos
Autores principales: Marshall, John M., Buchman, Anna, Sánchez C., Héctor M., Akbari, Omar S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476637/
https://www.ncbi.nlm.nih.gov/pubmed/28630470
http://dx.doi.org/10.1038/s41598-017-02744-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476637/
https://www.ncbi.nlm.nih.gov/pubmed/28630470
http://dx.doi.org/10.1038/s41598-017-02744-7

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