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Functional Evaluation of a Bioartificial Liver Support System Using Immobilized Hepatocyte Spheroids in a Porcine Model of Acute Liver Failure

Bioartificial livers (BAL) may offer acute liver failure (ALF) patients an opportunity for cure without liver transplantation. We evaluated the efficacy of a spheroid-based BAL system, containing aggregates of porcine hepatocytes, in a porcine model of ALF. ALF pigs were divided into three groups. T...

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Detalles Bibliográficos
Autores principales: Lee, Ji-Hyun, Lee, Doo-Hoon, Lee, Sanghoon, Kwon, Choon Hyuck David, Ryu, Jae-Nam, Noh, Jeong-Kwon, Jang, In Keun, Park, Hey-Jung, Yoon, Hee-Hoon, Park, Jung-Keug, Kim, Young-Jin, Kim, Sung-Koo, Lee, Suk-Koo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476639/
https://www.ncbi.nlm.nih.gov/pubmed/28630420
http://dx.doi.org/10.1038/s41598-017-03424-2