Cargando…

Impact of Antigen Density on the Binding Mechanism of IgG Antibodies

The density and distribution pattern of epitopes at the surface of pathogens have a profound impact on immune responses. Although multiple lines of evidence highlight the significance of antigen surface density for antibody binding, a quantitative description of its effect on recognition mechanisms...

Descripción completa

Detalles Bibliográficos
Autores principales: Hadzhieva, Maya, Pashov, Anastas D., Kaveri, Srinivas, Lacroix-Desmazes, Sébastien, Mouquet, Hugo, Dimitrov, Jordan D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476644/
https://www.ncbi.nlm.nih.gov/pubmed/28630473
http://dx.doi.org/10.1038/s41598-017-03942-z