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Acute administration of catalase targeted to ICAM-1 attenuates neuropathology in experimental traumatic brain injury

Traumatic brain injury (TBI) contributes to one third of injury related deaths in the US. Treatment strategies for TBI are supportive, and the pathophysiology is not fully understood. Secondary mechanisms of injury in TBI, such as oxidative stress and inflammation, are points at which intervention m...

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Detalles Bibliográficos
Autores principales: Lutton, Evan M., Razmpour, Roshanak, Andrews, Allison M., Cannella, Lee Anne, Son, Young-Jin, Shuvaev, Vladimir V., Muzykantov, Vladimir R., Ramirez, Servio H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476649/
https://www.ncbi.nlm.nih.gov/pubmed/28630485
http://dx.doi.org/10.1038/s41598-017-03309-4