A genome-wide association study of anorexia nervosa suggests a risk locus implicated in dysregulated leptin signaling

We conducted a genome-wide association study (GWAS) of anorexia nervosa (AN) using a stringently defined phenotype. Analysis of phenotypic variability led to the identification of a specific genetic risk factor that approached genome-wide significance (rs929626 in EBF1 (Early B-Cell Factor 1); P = 2...

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Detalles Bibliográficos
Autores principales: Li, Dong, Chang, Xiao, Connolly, John J., Tian, Lifeng, Liu, Yichuan, Bhoj, Elizabeth J., Robinson, Nora, Abrams, Debra, Li, Yun R., Bradfield, Jonathan P., Kim, Cecilia E., Li, Jin, Wang, Fengxiang, Snyder, James, Lemma, Maria, Hou, Cuiping, Wei, Zhi, Guo, Yiran, Qiu, Haijun, Mentch, Frank D., Thomas, Kelly A., Chiavacci, Rosetta M., Cone, Roger, Li, Bingshan, Sleiman, Patrick A., Hakonarson, Hakon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476671/
https://www.ncbi.nlm.nih.gov/pubmed/28630421
http://dx.doi.org/10.1038/s41598-017-01674-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476671/
https://www.ncbi.nlm.nih.gov/pubmed/28630421
http://dx.doi.org/10.1038/s41598-017-01674-8

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