The role of Antibody Vκ Framework 3 region towards Antigen binding: Effects on recombinant production and Protein L binding

Antibody research has traditionally focused on heavy chains, often neglecting the important complementary role of light chains in antibody formation and secretion. In the light chain, the complementarity-determining region 3 (VL-CDR3) is specifically implicated in disease states. By modulating VL-CD...

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Detalles Bibliográficos
Autores principales: Su, Chinh Tran-To, Ling, Wei-Li, Lua, Wai-Heng, Poh, Jun-Jie, Gan, Samuel Ken-En
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476676/
https://www.ncbi.nlm.nih.gov/pubmed/28630463
http://dx.doi.org/10.1038/s41598-017-02756-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476676/
https://www.ncbi.nlm.nih.gov/pubmed/28630463
http://dx.doi.org/10.1038/s41598-017-02756-3

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