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The role of Antibody Vκ Framework 3 region towards Antigen binding: Effects on recombinant production and Protein L binding
Antibody research has traditionally focused on heavy chains, often neglecting the important complementary role of light chains in antibody formation and secretion. In the light chain, the complementarity-determining region 3 (VL-CDR3) is specifically implicated in disease states. By modulating VL-CD...
Autores principales: | Su, Chinh Tran-To, Ling, Wei-Li, Lua, Wai-Heng, Poh, Jun-Jie, Gan, Samuel Ken-En |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476676/ https://www.ncbi.nlm.nih.gov/pubmed/28630463 http://dx.doi.org/10.1038/s41598-017-02756-3 |
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