Cargando…

Activation of D1R/PKA/mTOR signaling cascade in medial prefrontal cortex underlying the antidepressant effects of l-SPD

Major depressive disorder (MDD) is a common neuropsychiatric disorder characterized by diverse symptoms. Although several antidepressants can influence dopamine system in the medial prefrontal cortex (mPFC), but the role of D1R or D2R subtypes of dopamine receptor during anti-depression process is s...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Bing, Guo, Fei, Ma, Yuqin, Song, Yingcai, Lin, Rong, Shen, Fu-Yi, Jin, Guo-Zhang, Li, Yang, Liu, Zhi-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476681/
https://www.ncbi.nlm.nih.gov/pubmed/28630404
http://dx.doi.org/10.1038/s41598-017-03680-2