Cargando…

Activation of D1R/PKA/mTOR signaling cascade in medial prefrontal cortex underlying the antidepressant effects of l-SPD

Major depressive disorder (MDD) is a common neuropsychiatric disorder characterized by diverse symptoms. Although several antidepressants can influence dopamine system in the medial prefrontal cortex (mPFC), but the role of D1R or D2R subtypes of dopamine receptor during anti-depression process is s...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Bing, Guo, Fei, Ma, Yuqin, Song, Yingcai, Lin, Rong, Shen, Fu-Yi, Jin, Guo-Zhang, Li, Yang, Liu, Zhi-Qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476681/ https://www.ncbi.nlm.nih.gov/pubmed/28630404 http://dx.doi.org/10.1038/s41598-017-03680-2

Ejemplares similares

Activation of mTORC1 Signaling Cascade in Hippocampus and Medial Prefrontal Cortex Is Required for Antidepressant Actions of Vortioxetine in Mice
por: Li, Wei-Yu, et al.
Publicado: (2023)

Insufficiency of ventral hippocampus to medial prefrontal cortex transmission explains antidepressant non-response
por: Papp, Mariusz, et al.
Publicado: (2021)

The endogenous opioid system in the medial prefrontal cortex mediates ketamine’s antidepressant-like actions
por: Pittenger, Christopher, et al.
Publicado: (2023)

Aggression Results in the Phosphorylation of ERK1/2 in the Nucleus Accumbens and the Dephosphorylation of mTOR in the Medial Prefrontal Cortex in Female Syrian Hamsters
por: Borland, Johnathan M., et al.
Publicado: (2023)

Repeated Nitrous Oxide Exposure Exerts Antidepressant-Like Effects Through Neuronal Nitric Oxide Synthase Activation in the Medial Prefrontal Cortex
por: Liu, Wei, et al.
Publicado: (2020)

A Medial Prefrontal Cortex Cell Type Necessary and Sufficient for a Rapid Antidepressant Response
por: Hare, Brendan D., et al.
Publicado: (2019)

Optogenetic stimulation of medial prefrontal cortex Drd1 neurons produces rapid and long-lasting antidepressant effects
por: Hare, Brendan D., et al.
Publicado: (2019)

Attention deficits and hyperactivity following inhibition of cAMP-dependent protein kinase (PKA) within the medial prefrontal cortex of rats
por: Paine, Tracie A., et al.
Publicado: (2009)

IGF-1 release in the medial prefrontal cortex mediates the rapid and sustained antidepressant-like actions of ketamine
por: Deyama, Satoshi, et al.
Publicado: (2022)

PKA activation and endothelial claudin-5 breakdown in the schizophrenic prefrontal cortex
por: Nishiura, Keisuke, et al.
Publicado: (2017)

Role of AC-cAMP-PKA Cascade in Antidepressant Action of Electroacupuncture Treatment in Rats
por: Liu, Jian-hua, et al.
Publicado: (2012)

Role of 5-HT(1A) Receptor Stimulation in the Medial Prefrontal Cortex in the Sustained Antidepressant Effects of Ketamine
por: Fukumoto, Kenichi, et al.
Publicado: (2017)

Elevated O-GlcNAcylation induces an antidepressant-like phenotype and decreased inhibitory transmission in medial prefrontal cortex
por: Cho, Yoonjeong, et al.
Publicado: (2020)

The amygdala–insula–medial prefrontal cortex–lateral prefrontal cortex pathway and its disorders
por: Ben Shalom, Dorit
Publicado: (2022)

Medial prefrontal cortex as an action-outcome predictor
por: Alexander, William H., et al.
Publicado: (2011)

Behavioral control, the medial prefrontal cortex, and resilience
por: Maier, Steven F., et al.
Publicado: (2006)

Is the Medial Prefrontal Cortex Necessary for Theory of Mind?
por: Otti, Alexander, et al.
Publicado: (2015)

Optogenetic dissection of medial prefrontal cortex circuitry
por: Riga, Danai, et al.
Publicado: (2014)

Probing subicular inputs to the medial prefrontal cortex
por: Beerens, Sanne, et al.
Publicado: (2021)

Regulation of extracellular progranulin in medial prefrontal cortex
por: Kaplelach, Azariah K., et al.
Publicado: (2023)

Pathway interactions between MAPKs, mTOR, PKA, and the glucocorticoid receptor in lymphoid cells
por: Miller, Aaron L, et al.
Publicado: (2007)

Age attenuates the transcriptional changes that occur with sleep in the medial prefrontal cortex
por: Guo, Xiaofeng, et al.
Publicado: (2019)

The role of medial prefrontal cortex in early social cognition
por: Grossmann, Tobias
Publicado: (2013)

Segregation of the human medial prefrontal cortex in social cognition
por: Bzdok, Danilo, et al.
Publicado: (2013)

Evidence for Competition for Target Innervation in the Medial Prefrontal Cortex
por: Guirado, Ramon, et al.
Publicado: (2016)

The Role of the Medial Prefrontal Cortex in the Conditioning and Extinction of Fear
por: Giustino, Thomas F., et al.
Publicado: (2015)

The role of the medial prefrontal cortex in trace fear extinction
por: Kwapis, Janine L., et al.
Publicado: (2015)

Medial Prefrontal Cortex: Adding Value to Imagined Scenarios
por: Lin, Wen-Jing, et al.
Publicado: (2015)

Noradrenergic control of error perseveration in medial prefrontal cortex
por: Caetano, Marcelo S., et al.
Publicado: (2013)

The role of the medial prefrontal cortex in cognition, ageing and dementia
por: Jobson, Dan D, et al.
Publicado: (2021)

Dopamine Modulates Adaptive Forgetting in Medial Prefrontal Cortex
por: Gallo, Francisco Tomás, et al.
Publicado: (2022)

Defining the interconnectivity of the medial prefrontal cortex and ventral midbrain
por: Hui, May, et al.
Publicado: (2022)

Metabolite-related antidepressant action of diterpene ginkgolides in the prefrontal cortex
por: Hu, Qingchuan, et al.
Publicado: (2018)

mTOR Signaling Cascade in Psoriatic Disease: Double Kinase mTOR Inhibitor a Novel Therapeutic Target
por: Raychaudhuri, Smriti K, et al.
Publicado: (2014)

Medial Prefrontal Cortex to Medial Septum Pathway Activation Improves Cognitive Flexibility in Rats
por: Bortz, David M, et al.
Publicado: (2023)

Reward-related activity in the medial prefrontal cortex is driven by consumption
por: Horst, Nicole K., et al.
Publicado: (2013)

Control of Intermale Aggression by Medial Prefrontal Cortex Activation in the Mouse
por: Takahashi, Aki, et al.
Publicado: (2014)

A general role for medial prefrontal cortex in event prediction
por: Alexander, William H., et al.
Publicado: (2014)

The World According to Me: Personal Relevance and the Medial Prefrontal Cortex
por: Abraham, Anna
Publicado: (2013)

Medial prefrontal cortex stimulation modulates the processing of conditioned fear
por: Guhn, Anne, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_j0boklgnet7stgma3qar6173td