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PI3K/AKT/mTOR pathway promotes progestin resistance in endometrial cancer cells by inhibition of autophagy

Endometrial cancer (EC) is now one of the most common malignant tumors in young women. In all, 90% of young patients with EC have a high expression of progesterone recep tor, can be treated with progestin, and have very good prognosis. However, some of the young EC patients are resistant to progesti...

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Detalles Bibliográficos
Autores principales: Liu, Hua, Zhang, Liqin, Zhang, Xuyan, Cui, Zhumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476755/
https://www.ncbi.nlm.nih.gov/pubmed/28652768
http://dx.doi.org/10.2147/OTT.S95267