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Combination of azacitidine and trichostatin A decreased the tumorigenic potential of lung cancer cells

PURPOSE: This study aims to investigate the possibility of using epigenetic inhibitors against lung cancer. METHODS: The changes in the proliferation of human lung cancer cells, NCI-H1975 and NCI-H1299 cells, treated with various doses of inhibitors of DNA methyltransferase (azacitidine [5-AZA]) or...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Yin, Wei, Wu, Fengying, Fan, Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476757/
https://www.ncbi.nlm.nih.gov/pubmed/28652781
http://dx.doi.org/10.2147/OTT.S136218