A DNA dual lock-and-key strategy for cell-subtype-specific siRNA delivery

The efficient and precise delivery of siRNA to target cells is critical to successful gene therapy. While novel nanomaterials enhance delivery efficiency, it still remains challenging for precise gene delivery to overcome nonspecific adsorption and off-target effect. Here we design a dual lock-and-k...

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Detalles Bibliográficos
Autores principales: Ren, Kewei, Liu, Ying, Wu, Jie, Zhang, Yue, Zhu, Jing, Yang, Min, Ju, Huangxian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476801/
https://www.ncbi.nlm.nih.gov/pubmed/27882923
http://dx.doi.org/10.1038/ncomms13580

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476801/
https://www.ncbi.nlm.nih.gov/pubmed/27882923
http://dx.doi.org/10.1038/ncomms13580

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