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Anorexia‐cachexia syndrome in hepatoma tumour‐bearing rats requires the area postrema but not vagal afferents and is paralleled by increased MIC‐1/GDF15

BACKGROUND: The cancer‐anorexia‐cachexia syndrome (CACS) negatively affects survival and therapy success in cancer patients. Inflammatory mediators and tumour‐derived factors are thought to play an important role in the aetiology of CACS. However, the central and peripheral mechanisms contributing t...

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Detalles Bibliográficos
Autores principales: Borner, Tito, Arnold, Myrtha, Ruud, Johan, Breit, Samuel N., Langhans, Wolfgang, Lutz, Thomas A., Blomqvist, Anders, Riediger, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476861/
https://www.ncbi.nlm.nih.gov/pubmed/28025863
http://dx.doi.org/10.1002/jcsm.12169