Apolipoprotein E - A Multifunctional Protein with Implications in Various Pathologies as a Result of Its Structural Features

Apolipoprotein E (apoE), a 34 kDa glycoprotein, mediates hepatic and extrahepatic uptake of plasma lipoproteins and cholesterol efflux from lipid-laden macrophages. In humans, three structural different apoE isoforms occur, with subsequent functional changes and pathological consequences. Here, we r...

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Detalles Bibliográficos
Autores principales: Tudorache, Irina Florina, Trusca, Violeta Georgeta, Gafencu, Anca Violeta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Research Network of Computational and Structural Biotechnology 2017
Materias:
Mini Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476973/
https://www.ncbi.nlm.nih.gov/pubmed/28660014
http://dx.doi.org/10.1016/j.csbj.2017.05.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476973/
https://www.ncbi.nlm.nih.gov/pubmed/28660014
http://dx.doi.org/10.1016/j.csbj.2017.05.003

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