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Apolipoprotein E - A Multifunctional Protein with Implications in Various Pathologies as a Result of Its Structural Features
Apolipoprotein E (apoE), a 34 kDa glycoprotein, mediates hepatic and extrahepatic uptake of plasma lipoproteins and cholesterol efflux from lipid-laden macrophages. In humans, three structural different apoE isoforms occur, with subsequent functional changes and pathological consequences. Here, we r...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5476973/ https://www.ncbi.nlm.nih.gov/pubmed/28660014 http://dx.doi.org/10.1016/j.csbj.2017.05.003 |