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Accelerating chemoselective peptide bond formation using bis(2-selenylethyl)amido peptide selenoester surrogates

Given the potential of peptide selenoesters for protein total synthesis and the paucity of methods for the synthesis of these sensitive peptide derivatives, we sought to explore the usefulness of the bis(2-selenylethyl)amido (SeEA) group, i.e. the selenium analog of the bis(2-sulfanylethyl)amido (SE...

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Detalles Bibliográficos
Autores principales: Raibaut, Laurent, Cargoët, Marine, Ollivier, Nathalie, Chang, Yun Min, Drobecq, Hervé, Boll, Emmanuelle, Desmet, Rémi, Monbaliu, Jean-Christophe M., Melnyk, Oleg
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477010/
https://www.ncbi.nlm.nih.gov/pubmed/28660038
http://dx.doi.org/10.1039/c5sc03459k