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Enantioselective assembly of tertiary stereocenters via multicomponent chemoselective cross-coupling of geminal chloro(iodo)alkanes

Tertiary stereocenters represent a ubiquitous and highly important motif in many pharmaceutically active compounds and natural products. Development of efficient and straightforward approaches to their enantioselective construction from readily available simple substrates is an important yet challen...

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Detalles Bibliográficos
Autores principales: Jiang, X., Kulbitski, K., Nisnevich, G., Gandelman, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477020/
https://www.ncbi.nlm.nih.gov/pubmed/28660053
http://dx.doi.org/10.1039/c5sc04378f