Conjugating a groove-binding motif to an Ir(iii) complex for the enhancement of G-quadruplex probe behavior

In this study, the reported G-quadruplex groove binder benzo[d,e]isoquinoline was linked to a cyclometallated Ir(iii) complex to generate a highly selective DNA probe 1 that retains the favorable photophysical properties of the parent complex. The linked complex 1 showed advantages of both parent co...

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Detalles Bibliográficos
Autores principales: Wang, Modi, Mao, Zhifeng, Kang, Tian-Shu, Wong, Chun-Yuen, Mergny, Jean-Louis, Leung, Chung-Hang, Ma, Dik-Lung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2016
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477052/
https://www.ncbi.nlm.nih.gov/pubmed/28660021
http://dx.doi.org/10.1039/c6sc00001k

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477052/
https://www.ncbi.nlm.nih.gov/pubmed/28660021
http://dx.doi.org/10.1039/c6sc00001k

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