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Adoptive cell therapy using PD-1(+) myeloma-reactive T cells eliminates established myeloma in mice

BACKGROUND: Adoptive cellular therapy (ACT) with cancer antigen-reactive T cells following lymphodepletive pre-conditioning has emerged as a potentially curative therapy for patients with advanced cancers. However, identification and enrichment of appropriate T cell subsets for cancer eradication re...

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Detalles Bibliográficos
Autores principales: Jing, Weiqing, Gershan, Jill A., Blitzer, Grace C., Palen, Katie, Weber, James, McOlash, Laura, Riese, Matthew, Johnson, Bryon D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477110/
https://www.ncbi.nlm.nih.gov/pubmed/28642819
http://dx.doi.org/10.1186/s40425-017-0256-z