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Transcriptomic profiles of aging in naïve and memory CD4(+) cells from mice

BACKGROUND: CD4+ T cells can be broadly divided into naïve and memory subsets, each of which are differentially impaired by the aging process. It is unclear if and how these differences are reflected at the transcriptomic level. We performed microarray profiling on RNA derived from naïve (CD44(low))...

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Detalles Bibliográficos
Autores principales: Taylor, Jackson, Reynolds, Lindsay, Hou, Li, Lohman, Kurt, Cui, Wei, Kritchevsky, Stephen, McCall, Charles, Liu, Yongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477126/
https://www.ncbi.nlm.nih.gov/pubmed/28642803
http://dx.doi.org/10.1186/s12979-017-0092-5