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Targeting VEGFR-3/-2 signaling pathways with AD0157: a potential strategy against tumor-associated lymphangiogenesis and lymphatic metastases

BACKGROUND: Lymphatic metastasis is one of the leading causes of death in patients with different types of cancer and is the main prognostic factor for the disease survival. The formation of new lymphatic vessels (lymphangiogenesis) in primary tumors facilitates tumor cell dissemination to regional...

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Detalles Bibliográficos
Autores principales: García-Caballero, Melissa, Paupert, Jenny, Blacher, Silvia, Van de Velde, Maureen, Quesada, Ana Rodríguez, Medina, Miguel Angel, Noël, Agnès
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477162/
https://www.ncbi.nlm.nih.gov/pubmed/28629427
http://dx.doi.org/10.1186/s13045-017-0484-1