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Targeting VEGFR-3/-2 signaling pathways with AD0157: a potential strategy against tumor-associated lymphangiogenesis and lymphatic metastases
BACKGROUND: Lymphatic metastasis is one of the leading causes of death in patients with different types of cancer and is the main prognostic factor for the disease survival. The formation of new lymphatic vessels (lymphangiogenesis) in primary tumors facilitates tumor cell dissemination to regional...
Autores principales: | García-Caballero, Melissa, Paupert, Jenny, Blacher, Silvia, Van de Velde, Maureen, Quesada, Ana Rodríguez, Medina, Miguel Angel, Noël, Agnès |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477162/ https://www.ncbi.nlm.nih.gov/pubmed/28629427 http://dx.doi.org/10.1186/s13045-017-0484-1 |
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