Cargando…

SUMOylation Is an Inhibitory Constraint that Regulates the Prion-like Aggregation and Activity of CPEB3

Protein synthesis is crucial for the maintenance of long-term-memory-related synaptic plasticity. The prion-like cytoplasmic polyadenylation element-binding protein 3 (CPEB3) regulates the translation of several mRNAs important for long-term synaptic plasticity in the hippocampus. Here, we provide e...

Descripción completa

Detalles Bibliográficos
Autores principales: Drisaldi, Bettina, Colnaghi, Luca, Fioriti, Luana, Rao, Nishta, Myers, Cory, Snyder, Anna M., Metzger, Daniel J., Tarasoff, Jenna, Konstantinov, Edward, Fraser, Paul E., Manley, James L., Kandel, Eric R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477225/
https://www.ncbi.nlm.nih.gov/pubmed/26074071
http://dx.doi.org/10.1016/j.celrep.2015.04.061