Fibroblast paracrine TNF-α signaling elevates integrin A5 expression in idiopathic pulmonary fibrosis (IPF)

BACKGROUND: Idiopathic pulmonary fibrosis (IPF) is a progressive lung disease with a poor prognosis. Inflammatory cytokines play a significant role in IPF pathology. However, the fibroblast itself is also believed to be the primary effector in IPF. We hypothesized that the fibroblasts themselves sec...

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Detalles Bibliográficos
Autores principales: Epstein Shochet, Gali, Brook, Elizabetha, Israeli-Shani, Lilach, Edelstein, Evgeny, Shitrit, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477311/
https://www.ncbi.nlm.nih.gov/pubmed/28629363
http://dx.doi.org/10.1186/s12931-017-0606-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5477311/
https://www.ncbi.nlm.nih.gov/pubmed/28629363
http://dx.doi.org/10.1186/s12931-017-0606-x

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